NIVALIS THERAPEUTICS INC

CUSIP: 65481J109 Class: COM

MANUFACTURERS LIFE INSURANCE COMPANY, THE's Holding History (CIK: 0000928047)

Note: Option positions (PUT/CALL) are excluded.

Q2 2017
Shares 876 Value ($000) $2 Avg Close — Range —
Q1 2017
Shares 948 Value ($000) $3 Avg Close — Range —
Q4 2016
Shares 948 Value ($000) $2 Avg Close — Range —
Q3 2016
Shares 948 Value ($000) $8 Avg Close — Range —
Q2 2016
Shares 948 Value ($000) $4 Avg Close — Range —
Q1 2016
Shares 2,129 Value ($000) $9 Avg Close — Range —