NIVALIS THERAPEUTICS INC

CUSIP: 65481J109 Class: COM

D. E. Shaw & Co., Inc.'s Holding History (CIK: 0001009207)

Note: Option positions (PUT/CALL) are excluded.

Q3 2016
Shares 31,521 Value ($000) $256 Avg Close — Range —
Q2 2016
Shares 42,605 Value ($000) $196 Avg Close — Range —
Q1 2016
Shares 43,029 Value ($000) $179 Avg Close — Range —
Q4 2015
Shares 35,878 Value ($000) $278 Avg Close — Range —
Q3 2015
Shares 43,263 Value ($000) $561 Avg Close — Range —