NORTHWEST BIOTHERAPEUTICS IN

Ticker: NWBO CUSIP: 66737P600 Class: COM

SIMPLEX TRADING, LLC's Holding History (CIK: 0001488542)

Note: Option positions (PUT/CALL) are excluded.

Q3 2016

Shares 3,621 Value ($000) $1 Avg Close $0.46 Range $0.32 - $0.76

Q2 2016

Shares 1,221 Value ($000) $0 Avg Close $1.07 Range $0.55 - $1.84

Q1 2016

Shares 4,021 Value ($000) $5 Avg Close $1.97 Range $1.28 - $3.18

Q1 2015

Shares 56 Value ($000) $0 Avg Close $6.73 Range $5.25 - $8.76

Q4 2014

Shares 3,324 Value ($000) $18 Avg Close $5.12 Range $3.79 - $6.15

Period	Shares	Value ($000)	Average Close	Price Range
Q3 2016	3,621	$1	$0.46	$0.32 - $0.76
Q2 2016	1,221	$0	$1.07	$0.55 - $1.84
Q1 2016	4,021	$5	$1.97	$1.28 - $3.18
Q1 2015	56	$0	$6.73	$5.25 - $8.76
Q4 2014	3,324	$18	$5.12	$3.79 - $6.15