NOVAN INC

CUSIP: 66988N205 Class: Stock

TWO SIGMA ADVISERS, LP's Holding History (CIK: 0001478735)

Note: Option positions (PUT/CALL) are excluded.

Q2 2022
Shares 31,800 Value ($000) $74 Avg Close — Range —
Q1 2022
Shares 79,900 Value ($000) $315 Avg Close — Range —
Q4 2021
Shares 88,900 Value ($000) $371 Avg Close — Range —