NUVECTIS PHARMA INC

Ticker: NVCT CUSIP: 67080T108 Class: Common Stock

TWO SIGMA INVESTMENTS, LP's Holding History (CIK: 0001179392)

Note: Option positions (PUT/CALL) are excluded.

Q3 2025

Shares 18,435 Value ($000) $111 Avg Close $6.87 Range $5.57 - $8.57

Q2 2025

Shares 18,135 Value ($000) $135 Avg Close $9.07 Range $7.37 - $11.52

Q1 2025

Shares 20,093 Value ($000) $196 Avg Close $7.20 Range $5.33 - $10.71

Q4 2024

Shares 18,570 Value ($000) $100 Avg Close $6.26 Range $4.44 - $11.80

Q3 2024

Shares 26,785 Value ($000) $168 Avg Close $6.58 Range $5.85 - $7.60

Q2 2024

Shares 13,044 Value ($000) $83 Avg Close $6.80 Range $5.85 - $8.49

Q4 2023

Shares 22,771 Value ($000) $190 Avg Close $8.92 Range $7.50 - $13.15

Period	Shares	Value ($000)	Average Close	Price Range
Q3 2025	18,435	$111	$6.87	$5.57 - $8.57
Q2 2025	18,135	$135	$9.07	$7.37 - $11.52
Q1 2025	20,093	$196	$7.20	$5.33 - $10.71
Q4 2024	18,570	$100	$6.26	$4.44 - $11.80
Q3 2024	26,785	$168	$6.58	$5.85 - $7.60
Q2 2024	13,044	$83	$6.80	$5.85 - $8.49
Q4 2023	22,771	$190	$8.92	$7.50 - $13.15