ONKURE THERAPEUTICS INC

Ticker: OKUR CUSIP: 68277Q105 Class: Com

TWO SIGMA ADVISERS, LP's Holding History (CIK: 0001478735)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 26,608 Value ($000) $77 Avg Close $2.99 Range $2.53 - $3.63

Q3 2025

Shares 26,608 Value ($000) $73 Avg Close $2.48 Range $1.91 - $2.98

Q2 2025

Shares 26,828 Value ($000) $64 Avg Close $2.62 Range $1.70 - $4.32

Q1 2025

Shares 27,628 Value ($000) $119 Avg Close $5.62 Range $4.26 - $9.40

Q4 2024

Shares 14,228 Value ($000) $122 Avg Close $15.14 Range $7.69 - $20.00

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	26,608	$77	$2.99	$2.53 - $3.63
Q3 2025	26,608	$73	$2.48	$1.91 - $2.98
Q2 2025	26,828	$64	$2.62	$1.70 - $4.32
Q1 2025	27,628	$119	$5.62	$4.26 - $9.40
Q4 2024	14,228	$122	$15.14	$7.69 - $20.00