OPHTHOTECH CORP

CUSIP: 683745103 Class: COM

PRICE T ROWE ASSOCIATES INC /MD/'s Holding History (CIK: 0000080255)

Note: Option positions (PUT/CALL) are excluded.

Q4 2016
Shares 578,795 Value ($000) $2,796 Avg Close — Range —
Q3 2016
Shares 2,055,762 Value ($000) $94,832 Avg Close — Range —
Q2 2016
Shares 1,767,562 Value ($000) $90,199 Avg Close — Range —
Q1 2016
Shares 1,768,227 Value ($000) $74,743 Avg Close — Range —
Q4 2015
Shares 1,639,927 Value ($000) $128,783 Avg Close — Range —
Q3 2015
Shares 1,936,814 Value ($000) $78,480 Avg Close — Range —
Q2 2015
Shares 2,011,408 Value ($000) $104,714 Avg Close — Range —
Q1 2015
Shares 1,400,966 Value ($000) $65,187 Avg Close — Range —
Q4 2014
Shares 1,370,042 Value ($000) $61,474 Avg Close — Range —
Q3 2014
Shares 1,368,374 Value ($000) $53,271 Avg Close — Range —
Q2 2014
Shares 1,192,547 Value ($000) $50,457 Avg Close — Range —
Q1 2014
Shares 995,823 Value ($000) $35,591 Avg Close — Range —
Q4 2013
Shares 829,123 Value ($000) $26,822 Avg Close — Range —