OPHTHOTECH CORP

CUSIP: 683745103 Class: COM

MARSHALL WACE, LLP's Holding History (CIK: 0001318757)

Note: Option positions (PUT/CALL) are excluded.

Q2 2016
Shares 117,872 Value ($000) $6,015 Avg Close — Range —
Q1 2016
Shares 139,298 Value ($000) $5,888 Avg Close — Range —
Q4 2015
Shares 117,964 Value ($000) $9,264 Avg Close — Range —
Q3 2015
Shares 164,447 Value ($000) $6,663 Avg Close — Range —
Q2 2015
Shares 59,144 Value ($000) $3,079 Avg Close — Range —
Q4 2014
Shares 68,470 Value ($000) $3,072 Avg Close — Range —
Q1 2014
Shares 8,400 Value ($000) $300 Avg Close — Range —