OPHTHOTECH CORP

CUSIP: 683745103 Class: COM

RA CAPITAL MANAGEMENT, L.P.'s Holding History (CIK: 0001346824)

Note: Option positions (PUT/CALL) are excluded.

Q4 2014
Shares 310,554 Value ($000) $13,935 Avg Close — Range —
Q3 2014
Shares 588,941 Value ($000) $22,927 Avg Close — Range —
Q2 2014
Shares 527,941 Value ($000) $22,337 Avg Close — Range —
Q1 2014
Shares 1,737,856 Value ($000) $61,998 Avg Close — Range —
Q4 2013
Shares 1,600,455 Value ($000) $51,775 Avg Close — Range —