OPHTHOTECH CORP

CUSIP: 683745103 Class: COM

GAM Holding AG's Holding History (CIK: 0001438848)

Note: Option positions (PUT/CALL) are excluded.

Q4 2016

Shares 60,300 Value ($000) $291 Avg Close — Range —

Q3 2016

Shares 31,500 Value ($000) $1,453 Avg Close — Range —

Q2 2016

Shares 63,000 Value ($000) $3,215 Avg Close — Range —

Q1 2016

Shares 31,500 Value ($000) $1,332 Avg Close — Range —

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2016	60,300	$291	—	—
Q3 2016	31,500	$1,453	—	—
Q2 2016	63,000	$3,215	—	—
Q1 2016	31,500	$1,332	—	—