OPKO Health Inc.

CUSIP: 68375NAA1 Class: NOTE 3.0% 2/1/33

TANG CAPITAL MANAGEMENT LLC's Holding History (CIK: 0001232621)

Note: Option positions (PUT/CALL) are excluded.

Q3 2014
Shares 14,000,000 Value ($000) $18,760 Avg Close — Range —
Q2 2014
Shares 14,000,000 Value ($000) $18,739 Avg Close — Range —
Q1 2014
Shares 14,000,000 Value ($000) $19,040 Avg Close — Range —
Q4 2013
Shares 14,000,000 Value ($000) $17,050 Avg Close — Range —
Q3 2013
Shares 25,000,000 Value ($000) $30,939 Avg Close — Range —
Q2 2013
Shares 29,500,000 Value ($000) $30,795 Avg Close — Range —