OPTINOSE INC

CUSIP: 68404V100 Class: Common Stock

TWO SIGMA ADVISERS, LP's Holding History (CIK: 0001478735)

Note: Option positions (PUT/CALL) are excluded.

Q3 2020
Shares 37,600 Value ($000) $147 Avg Close — Range —
Q2 2020
Shares 13,900 Value ($000) $103 Avg Close — Range —
Q1 2020
Shares 14,400 Value ($000) $65 Avg Close — Range —
Q2 2019
Shares 13,300 Value ($000) $94 Avg Close — Range —
Q1 2019
Shares 22,000 Value ($000) $227 Avg Close — Range —
Q4 2018
Shares 21,800 Value ($000) $135 Avg Close — Range —