ORCHARD THERAPEUTICS PLC

CUSIP: 68570P101 Class: ADS

FMR LLC's Holding History (CIK: 0000315066)

Note: Option positions (PUT/CALL) are excluded.

Q4 2022
Shares 8,611,375 Value ($000) $3,195 Avg Close — Range —
Q3 2022
Shares 8,611,375 Value ($000) $4,306 Avg Close — Range —
Q2 2022
Shares 8,611,375 Value ($000) $5,031 Avg Close — Range —
Q1 2022
Shares 8,611,375 Value ($000) $6,131 Avg Close — Range —
Q4 2021
Shares 8,611,375 Value ($000) $11,367 Avg Close — Range —
Q3 2021
Shares 8,611,375 Value ($000) $19,806 Avg Close — Range —
Q2 2021
Shares 8,611,375 Value ($000) $37,804 Avg Close — Range —
Q1 2021
Shares 8,611,375 Value ($000) $62,519 Avg Close — Range —
Q4 2020
Shares 12,244,590 Value ($000) $52,897 Avg Close — Range —
Q3 2020
Shares 12,244,590 Value ($000) $50,325 Avg Close — Range —
Q2 2020
Shares 12,244,590 Value ($000) $73,468 Avg Close — Range —
Q1 2020
Shares 12,244,590 Value ($000) $92,202 Avg Close — Range —
Q4 2019
Shares 12,273,064 Value ($000) $168,755 Avg Close — Range —
Q3 2019
Shares 20,407,650 Value ($000) $242,443 Avg Close — Range —
Q2 2019
Shares 20,407,650 Value ($000) $285,503 Avg Close — Range —
Q1 2019
Shares 20,407,650 Value ($000) $364,889 Avg Close — Range —
Q4 2018
Shares 20,407,650 Value ($000) $321,012 Avg Close — Range —