ORCHARD THERAPEUTICS PLC

CUSIP: 68570P101 Class: ADS

MASSACHUSETTS FINANCIAL SERVICES CO /MA/'s Holding History (CIK: 0000912938)

Note: Option positions (PUT/CALL) are excluded.

Q2 2021
Shares 500,256 Value ($000) $2,196 Avg Close — Range —
Q1 2021
Shares 501,739 Value ($000) $3,643 Avg Close — Range —
Q4 2020
Shares 513,801 Value ($000) $2,220 Avg Close — Range —
Q3 2020
Shares 504,313 Value ($000) $2,073 Avg Close — Range —
Q2 2020
Shares 516,701 Value ($000) $3,100 Avg Close — Range —
Q1 2020
Shares 498,391 Value ($000) $3,753 Avg Close — Range —
Q4 2019
Shares 509,979 Value ($000) $7,012 Avg Close — Range —
Q3 2019
Shares 509,827 Value ($000) $6,057 Avg Close — Range —
Q2 2019
Shares 511,800 Value ($000) $7,160 Avg Close — Range —
Q1 2019
Shares 441,423 Value ($000) $7,893 Avg Close — Range —
Q4 2018
Shares 441,718 Value ($000) $6,948 Avg Close — Range —