ORCHARD THERAPEUTICS PLC

CUSIP: 68570P101 Class: ADS

OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AM's Holding History (CIK: 0001132716)

Note: Option positions (PUT/CALL) are excluded.

Q3 2022
Shares 432,978 Value ($000) $216,000 Avg Close — Range —
Q2 2022
Shares 1,093,924 Value ($000) $639,000 Avg Close — Range —