ORCHARD THERAPEUTICS PLC

CUSIP: 68570P101 Class: ADS

CANADA PENSION PLAN INVESTMENT BOARD's Holding History (CIK: 0001283718)

Note: Option positions (PUT/CALL) are excluded.

Q1 2020
Shares 29,558 Value ($000) $223 Avg Close — Range —
Q4 2019
Shares 105,174 Value ($000) $1,446 Avg Close — Range —