ORCHARD THERAPEUTICS PLC

CUSIP: 68570P101 Class: ADS

SG Americas Securities, LLC's Holding History (CIK: 0001313360)

Note: Option positions (PUT/CALL) are excluded.

Q1 2022
Shares 1,052,786 Value ($000) $750 Avg Close — Range —
Q4 2021
Shares 649,670 Value ($000) $858 Avg Close — Range —