ORCHARD THERAPEUTICS PLC

CUSIP: 68570P101 Class: ADS

MARSHALL WACE, LLP's Holding History (CIK: 0001318757)

Note: Option positions (PUT/CALL) are excluded.

Q4 2021
Shares 23,547 Value ($000) $31 Avg Close — Range —
Q3 2021
Shares 157,194 Value ($000) $361 Avg Close — Range —
Q2 2020
Shares 66,423 Value ($000) $399 Avg Close — Range —
Q4 2019
Shares 138,830 Value ($000) $1,909 Avg Close — Range —
Q3 2019
Shares 28,123 Value ($000) $334 Avg Close — Range —
Q2 2019
Shares 25,177 Value ($000) $352 Avg Close — Range —