ORCHARD THERAPEUTICS PLC

CUSIP: 68570P101 Class: ADS

EVENTIDE ASSET MANAGEMENT, LLC's Holding History (CIK: 0001442891)

Note: Option positions (PUT/CALL) are excluded.

Q1 2020
Shares 270,000 Value ($000) $2,033 Avg Close — Range —
Q4 2019
Shares 270,000 Value ($000) $3,713 Avg Close — Range —
Q3 2019
Shares 270,000 Value ($000) $3,208 Avg Close — Range —
Q2 2019
Shares 270,000 Value ($000) $3,777 Avg Close — Range —
Q1 2019
Shares 270,000 Value ($000) $4,828 Avg Close — Range —
Q4 2018
Shares 270,000 Value ($000) $4,247 Avg Close — Range —