ORCHARD THERAPEUTICS PLC

CUSIP: 68570P101 Class: ADS

Alyeska Investment Group, L.P.'s Holding History (CIK: 0001453072)

Note: Option positions (PUT/CALL) are excluded.

Q1 2019
Shares 56,986 Value ($000) $1,019 Avg Close — Range —
Q4 2018
Shares 111,250 Value ($000) $1,750 Avg Close — Range —