ORCHARD THERAPEUTICS PLC

CUSIP: 68570P101 Class: ADS

JANE STREET GROUP, LLC's Holding History (CIK: 0001595888)

Note: Option positions (PUT/CALL) are excluded.

Q4 2022
Shares 75,643 Value ($000) $28 Avg Close — Range —
Q3 2022
Shares 45,953 Value ($000) $23 Avg Close — Range —
Q4 2021
Shares 80,648 Value ($000) $106 Avg Close — Range —
Q3 2021
Shares 12,597 Value ($000) $29 Avg Close — Range —
Q1 2021
Shares 10,934 Value ($000) $79 Avg Close — Range —
Q4 2020
Shares 10,575 Value ($000) $46 Avg Close — Range —