ORCHARD THERAPEUTICS PLC

CUSIP: 68570P101 Class: ADS

Engineers Gate Manager LP's Holding History (CIK: 0001620220)

Note: Option positions (PUT/CALL) are excluded.

Q4 2021
Shares 30,326 Value ($000) $40 Avg Close — Range —
Q2 2020
Shares 30,500 Value ($000) $183 Avg Close — Range —
Q1 2020
Shares 13,000 Value ($000) $98 Avg Close — Range —