OREXIGEN THERAPEUTICS INC

CUSIP: 686164104 Class: COMMON STOCK

FRED ALGER MANAGEMENT, LLC's Holding History (CIK: 0000003520)

Note: Option positions (PUT/CALL) are excluded.

Q4 2014
Shares 2,430,038 Value ($000) $14,726 Avg Close — Range —
Q3 2014
Shares 1,127,753 Value ($000) $4,804 Avg Close — Range —
Q2 2014
Shares 1,528,031 Value ($000) $9,443 Avg Close — Range —
Q1 2014
Shares 1,779,759 Value ($000) $11,568 Avg Close — Range —
Q4 2013
Shares 1,795,189 Value ($000) $10,107 Avg Close — Range —
Q3 2013
Shares 1,462,527 Value ($000) $8,965 Avg Close — Range —
Q2 2013
Shares 1,466,565 Value ($000) $8,572 Avg Close — Range —