OREXIGEN THERAPEUTICS INC

CUSIP: 686164104 Class: COMMON STOCK

PRELUDE CAPITAL MANAGEMENT, LLC's Holding History (CIK: 0001387508)

Note: Option positions (PUT/CALL) are excluded.

Q4 2015
Shares 27,300 Value ($000) $47 Avg Close — Range —
Q3 2015
Shares 27,300 Value ($000) $58 Avg Close — Range —
Q2 2015
Shares 11,900 Value ($000) $59 Avg Close — Range —
Q1 2015
Shares 5,000 Value ($000) $39 Avg Close — Range —