OREXIGEN THERAPEUTICS INC

CUSIP: 686164104 Class: COMMON STOCK

PFM Health Sciences, LP's Holding History (CIK: 0001442756)

Note: Option positions (PUT/CALL) are excluded.

Q2 2015
Shares 5,278,672 Value ($000) $26,129 Avg Close — Range —
Q1 2015
Shares 2,870,492 Value ($000) $22,476 Avg Close — Range —
Q4 2014
Shares 3,179,762 Value ($000) $19,269 Avg Close — Range —
Q3 2014
Shares 4,838,324 Value ($000) $20,611 Avg Close — Range —
Q2 2014
Shares 4,604,958 Value ($000) $28,459 Avg Close — Range —
Q1 2014
Shares 5,129,129 Value ($000) $33,339 Avg Close — Range —
Q4 2013
Shares 5,047,119 Value ($000) $28,415 Avg Close — Range —
Q3 2013
Shares 3,583,342 Value ($000) $21,966 Avg Close — Range —
Q2 2013
Shares 3,646,260 Value ($000) $21,312 Avg Close — Range —
Q1 2013
Shares 2,280,053 Value ($000) $14,273 Avg Close — Range —