OSIRIS THERAPEUTICS INC NEW

CUSIP: 68827R108 Class: CMN

MANUFACTURERS LIFE INSURANCE COMPANY, THE's Holding History (CIK: 0000928047)

Note: Option positions (PUT/CALL) are excluded.

Q4 2018
Shares 130,077 Value ($000) $1,756 Avg Close — Range —
Q3 2018
Shares 641,224 Value ($000) $7,118 Avg Close — Range —
Q4 2016
Shares 1,053 Value ($000) $5 Avg Close — Range —
Q3 2016
Shares 1,053 Value ($000) $5 Avg Close — Range —
Q2 2016
Shares 1,053 Value ($000) $5 Avg Close — Range —
Q1 2016
Shares 13,929 Value ($000) $75 Avg Close — Range —
Q4 2015
Shares 13,353 Value ($000) $139 Avg Close — Range —
Q3 2015
Shares 13,109 Value ($000) $239 Avg Close — Range —
Q2 2015
Shares 12,883 Value ($000) $251 Avg Close — Range —
Q1 2015
Shares 13,679 Value ($000) $241 Avg Close — Range —
Q4 2014
Shares 13,173 Value ($000) $211 Avg Close — Range —
Q3 2014
Shares 12,704 Value ($000) $160 Avg Close — Range —
Q2 2014
Shares 13,171 Value ($000) $206 Avg Close — Range —
Q1 2014
Shares 13,532 Value ($000) $178 Avg Close — Range —
Q4 2013
Shares 12,493 Value ($000) $201 Avg Close — Range —
Q3 2013
Shares 13,981 Value ($000) $232 Avg Close — Range —
Q2 2013
Shares 14,468 Value ($000) $146 Avg Close — Range —