OSIRIS THERAPEUTICS INC NEW

CUSIP: 68827R108 Class: CMN

BAKER BROS. ADVISORS LP's Holding History (CIK: 0001263508)

Note: Option positions (PUT/CALL) are excluded.

Q4 2016
Shares 499,193 Value ($000) $2,451 Avg Close — Range —
Q3 2016
Shares 499,193 Value ($000) $2,476 Avg Close — Range —
Q2 2016
Shares 499,193 Value ($000) $2,541 Avg Close — Range —
Q1 2016
Shares 499,193 Value ($000) $2,850 Avg Close — Range —
Q4 2015
Shares 499,193 Value ($000) $5,182 Avg Close — Range —
Q3 2015
Shares 499,193 Value ($000) $9,220 Avg Close — Range —
Q2 2015
Shares 499,193 Value ($000) $9,714 Avg Close — Range —
Q1 2015
Shares 499,193 Value ($000) $8,776 Avg Close — Range —
Q4 2014
Shares 510,606 Value ($000) $8,165 Avg Close — Range —
Q3 2014
Shares 510,606 Value ($000) $6,429 Avg Close — Range —
Q2 2014
Shares 510,606 Value ($000) $7,976 Avg Close — Range —
Q1 2014
Shares 361,530 Value ($000) $4,747 Avg Close — Range —
Q4 2013
Shares 375,282 Value ($000) $6,035 Avg Close — Range —
Q3 2013
Shares 375,282 Value ($000) $6,245 Avg Close — Range —