OSIRIS THERAPEUTICS INC NEW

CUSIP: 68827R108 Class: CMN

TWO SIGMA ADVISERS, LP's Holding History (CIK: 0001478735)

Note: Option positions (PUT/CALL) are excluded.

Q3 2016
Shares 11,707 Value ($000) $58 Avg Close — Range —
Q2 2016
Shares 18,807 Value ($000) $96 Avg Close — Range —
Q1 2016
Shares 19,007 Value ($000) $109 Avg Close — Range —