OTONOMY INC

CUSIP: 68906L105 Class: COM

MANUFACTURERS LIFE INSURANCE COMPANY, THE's Holding History (CIK: 0000928047)

Note: Option positions (PUT/CALL) are excluded.

Q2 2018
Shares 1,511 Value ($000) $6 Avg Close — Range —
Q1 2018
Shares 11,118 Value ($000) $47 Avg Close — Range —
Q4 2017
Shares 22,377 Value ($000) $125 Avg Close — Range —
Q3 2017
Shares 982 Value ($000) $3 Avg Close — Range —
Q2 2017
Shares 23,105 Value ($000) $435 Avg Close — Range —
Q1 2017
Shares 20,329 Value ($000) $249 Avg Close — Range —
Q4 2016
Shares 17,453 Value ($000) $277 Avg Close — Range —
Q3 2016
Shares 17,289 Value ($000) $314 Avg Close — Range —
Q2 2016
Shares 17,547 Value ($000) $279 Avg Close — Range —
Q1 2016
Shares 11,489 Value ($000) $170 Avg Close — Range —
Q4 2015
Shares 10,315 Value ($000) $286 Avg Close — Range —
Q3 2015
Shares 10,093 Value ($000) $179 Avg Close — Range —
Q2 2015
Shares 9,911 Value ($000) $228 Avg Close — Range —
Q1 2015
Shares 5,683 Value ($000) $201 Avg Close — Range —
Q4 2014
Shares 5,310 Value ($000) $177 Avg Close — Range —