OTONOMY INC

CUSIP: 68906L105 Class: COM

D. E. Shaw & Co., Inc.'s Holding History (CIK: 0001009207)

Note: Option positions (PUT/CALL) are excluded.

Q4 2019
Shares 675,400 Value ($000) $2,587 Avg Close — Range —
Q3 2019
Shares 830,754 Value ($000) $1,985 Avg Close — Range —
Q2 2019
Shares 830,754 Value ($000) $2,285 Avg Close — Range —
Q1 2019
Shares 840,868 Value ($000) $2,211 Avg Close — Range —
Q4 2018
Shares 859,838 Value ($000) $1,591 Avg Close — Range —
Q3 2018
Shares 898,004 Value ($000) $2,469 Avg Close — Range —
Q2 2018
Shares 884,026 Value ($000) $3,403 Avg Close — Range —
Q1 2018
Shares 817,208 Value ($000) $3,433 Avg Close — Range —
Q4 2017
Shares 817,296 Value ($000) $4,536 Avg Close — Range —
Q3 2017
Shares 100,513 Value ($000) $327 Avg Close — Range —
Q2 2017
Shares 163,587 Value ($000) $3,084 Avg Close — Range —
Q1 2017
Shares 166,340 Value ($000) $2,038 Avg Close — Range —
Q4 2016
Shares 154,040 Value ($000) $2,449 Avg Close — Range —
Q3 2016
Shares 150,084 Value ($000) $2,730 Avg Close — Range —
Q2 2016
Shares 166,457 Value ($000) $2,643 Avg Close — Range —
Q1 2016
Shares 181,832 Value ($000) $2,713 Avg Close — Range —
Q4 2015
Shares 111,715 Value ($000) $3,100 Avg Close — Range —
Q3 2015
Shares 85,118 Value ($000) $1,516 Avg Close — Range —
Q2 2015
Shares 130,963 Value ($000) $3,011 Avg Close — Range —
Q1 2015
Shares 158,877 Value ($000) $5,618 Avg Close — Range —
Q4 2014
Shares 113,350 Value ($000) $3,778 Avg Close — Range —
Q3 2014
Shares 103,459 Value ($000) $2,483 Avg Close — Range —