OTONOMY INC

CUSIP: 68906L105 Class: COM

CLOUGH CAPITAL PARTNERS L P's Holding History (CIK: 0001276144)

Note: Option positions (PUT/CALL) are excluded.

Q4 2016
Shares 236,203 Value ($000) $3,756 Avg Close — Range —
Q3 2016
Shares 238,103 Value ($000) $4,331 Avg Close — Range —
Q2 2016
Shares 342,303 Value ($000) $5,436 Avg Close — Range —
Q1 2016
Shares 316,503 Value ($000) $4,722 Avg Close — Range —
Q4 2015
Shares 280,403 Value ($000) $7,781 Avg Close — Range —
Q3 2015
Shares 269,503 Value ($000) $4,800 Avg Close — Range —
Q2 2015
Shares 165,903 Value ($000) $3,814 Avg Close — Range —
Q1 2015
Shares 251,605 Value ($000) $8,897 Avg Close — Range —
Q4 2014
Shares 334,705 Value ($000) $11,156 Avg Close — Range —
Q3 2014
Shares 334,603 Value ($000) $8,030 Avg Close — Range —