OTONOMY INC

CUSIP: 68906L105 Class: COM

MARSHALL WACE, LLP's Holding History (CIK: 0001318757)

Note: Option positions (PUT/CALL) are excluded.

Q1 2016
Shares 280,927 Value ($000) $4,191 Avg Close — Range —
Q2 2015
Shares 60,930 Value ($000) $1,401 Avg Close — Range —
Q3 2014
Shares 32,500 Value ($000) $780 Avg Close — Range —