OVASCIENCE INC

CUSIP: 69014Q101 Class: COM

TWO SIGMA INVESTMENTS, LP's Holding History (CIK: 0001179392)

Note: Option positions (PUT/CALL) are excluded.

Q3 2018
Shares 33,640 Value ($000) $25 Avg Close — Range —
Q1 2018
Shares 33,911 Value ($000) $28 Avg Close — Range —
Q4 2017
Shares 244,118 Value ($000) $342 Avg Close — Range —
Q1 2015
Shares 16,678 Value ($000) $579 Avg Close — Range —