PACIFIC BIOSCIENCES CALIF IN

Ticker: PACB CUSIP: 69404D108 Class: COM

MANUFACTURERS LIFE INSURANCE COMPANY, THE's Holding History (CIK: 0000928047)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 82,527 Value ($000) $154 Avg Close $1.92 Range $1.26 - $2.73

Q3 2025

Shares 93,842 Value ($000) $120 Avg Close $1.35 Range $1.15 - $1.76

Q2 2025

Shares 100,914 Value ($000) $125 Avg Close $1.15 Range $0.85 - $1.49

Q1 2025

Shares 98,116 Value ($000) $116 Avg Close $1.53 Range $1.08 - $2.22

Q4 2024

Shares 292,459 Value ($000) $535 Avg Close $1.95 Range $1.42 - $2.72

Q3 2024

Shares 295,365 Value ($000) $502 Avg Close $1.64 Range $1.16 - $2.26

Q2 2024

Shares 329,815 Value ($000) $452 Avg Close $2.02 Range $1.25 - $3.85

Q1 2024

Shares 314,248 Value ($000) $1,178 Avg Close $5.86 Range $3.46 - $9.99

Q4 2023

Shares 326,477 Value ($000) $3,203 Avg Close $8.18 Range $5.74 - $10.65

Q3 2023

Shares 332,046 Value ($000) $2,773 Avg Close $11.43 Range $8.16 - $14.55

Q2 2023

Shares 283,306 Value ($000) $3,768 Avg Close $12.15 Range $9.85 - $14.30

Q1 2023

Shares 273,376 Value ($000) $3,166 Avg Close $9.94 Range $7.77 - $12.54

Q4 2022

Shares 253,329 Value ($000) $2,090 Avg Close $8.62 Range $5.46 - $12.37

Q3 2022

Shares 253,955 Value ($000) $1,440 Avg Close $5.74 Range $3.89 - $14.20

Q2 2022

Shares 256,852 Value ($000) $1,160 Avg Close $6.08 Range $3.85 - $10.48

Q1 2022

Shares 246,142 Value ($000) $2,331 Avg Close $11.51 Range $8.26 - $21.01

Q4 2021

Shares 98,444 Value ($000) $2,038 Avg Close $24.13 Range $18.26 - $31.10

Q3 2021

Shares 98,698 Value ($000) $2,522 Avg Close $29.63 Range $24.31 - $35.58

Q2 2021

Shares 108,314 Value ($000) $3,788 Avg Close $29.09 Range $20.22 - $37.42

Q1 2021

Shares 101,565 Value ($000) $3,383 Avg Close $35.00 Range $24.47 - $53.69

Q4 2020

Shares 104,827 Value ($000) $2,719 Avg Close $16.99 Range $9.97 - $29.73

Q3 2020

Shares 94,678 Value ($000) $934 Avg Close $5.76 Range $3.41 - $10.11

Q2 2020

Shares 88,386 Value ($000) $305 Avg Close $3.40 Range $2.54 - $4.22

Q1 2020

Shares 92,405 Value ($000) $283 Avg Close $4.09 Range $2.20 - $5.44

Q4 2019

Shares 85,973 Value ($000) $442 Avg Close $5.08 Range $4.37 - $5.69

Q3 2019

Shares 88,156 Value ($000) $460 Avg Close $5.59 Range $4.96 - $6.21

Q2 2019

Shares 88,295 Value ($000) $534 Avg Close $7.01 Range $5.80 - $7.50

Q1 2019

Shares 89,931 Value ($000) $650 Avg Close $7.23 Range $6.72 - $7.46

Q4 2018

Shares 80,805 Value ($000) $598 Avg Close $6.34 Range $3.90 - $7.84

Q3 2018

Shares 82,167 Value ($000) $445 Avg Close $4.29 Range $3.33 - $5.82

Q2 2018

Shares 95,341 Value ($000) $338 Avg Close $2.77 Range $2.02 - $4.09

Q1 2018

Shares 91,923 Value ($000) $189 Avg Close $2.60 Range $2.03 - $3.43

Q4 2017

Shares 84,180 Value ($000) $223 Avg Close $3.50 Range $2.51 - $5.58

Q3 2017

Shares 82,033 Value ($000) $431 Avg Close $4.30 Range $3.08 - $5.70

Q2 2017

Shares 70,533 Value ($000) $250 Avg Close $4.03 Range $3.11 - $5.43

Q1 2017

Shares 65,388 Value ($000) $339 Avg Close $4.89 Range $3.78 - $5.74

Q4 2016

Shares 56,358 Value ($000) $215 Avg Close $7.27 Range $3.76 - $9.28

Q3 2016

Shares 52,689 Value ($000) $473 Avg Close $8.36 Range $6.76 - $9.50

Q2 2016

Shares 53,368 Value ($000) $376 Avg Close $9.14 Range $6.79 - $10.75

Q1 2016

Shares 41,448 Value ($000) $362 Avg Close $9.83 Range $7.50 - $13.98

Q4 2015

Shares 44,225 Value ($000) $580 Avg Close $8.97 Range $4.26 - $14.00

Q3 2015

Shares 43,805 Value ($000) $161 Avg Close $4.89 Range $3.58 - $5.90

Q2 2015

Shares 43,360 Value ($000) $250 Avg Close $5.79 Range $5.11 - $6.55

Q1 2015

Shares 39,385 Value ($000) $230 Avg Close $6.90 Range $5.38 - $8.78

Q4 2014

Shares 37,901 Value ($000) $297 Avg Close $6.40 Range $4.52 - $8.10

Q3 2014

Shares 38,448 Value ($000) $189 Avg Close $5.23 Range $4.38 - $6.42

Q2 2014

Shares 38,291 Value ($000) $237 Avg Close $5.00 Range $3.87 - $6.65

Q1 2014

Shares 38,156 Value ($000) $204 Avg Close $6.32 Range $4.73 - $8.20

Q4 2013

Shares 39,542 Value ($000) $207 Avg Close $4.59 Range $3.47 - $5.95

Q3 2013

Shares 1,400 Value ($000) $8 Avg Close $3.47 Range $2.45 - $6.50

Q2 2013

Shares 960 Value ($000) $2 Avg Close $2.49 Range $1.95 - $2.94

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	82,527	$154	$1.92	$1.26 - $2.73
Q3 2025	93,842	$120	$1.35	$1.15 - $1.76
Q2 2025	100,914	$125	$1.15	$0.85 - $1.49
Q1 2025	98,116	$116	$1.53	$1.08 - $2.22
Q4 2024	292,459	$535	$1.95	$1.42 - $2.72
Q3 2024	295,365	$502	$1.64	$1.16 - $2.26
Q2 2024	329,815	$452	$2.02	$1.25 - $3.85
Q1 2024	314,248	$1,178	$5.86	$3.46 - $9.99
Q4 2023	326,477	$3,203	$8.18	$5.74 - $10.65
Q3 2023	332,046	$2,773	$11.43	$8.16 - $14.55
Q2 2023	283,306	$3,768	$12.15	$9.85 - $14.30
Q1 2023	273,376	$3,166	$9.94	$7.77 - $12.54
Q4 2022	253,329	$2,090	$8.62	$5.46 - $12.37
Q3 2022	253,955	$1,440	$5.74	$3.89 - $14.20
Q2 2022	256,852	$1,160	$6.08	$3.85 - $10.48
Q1 2022	246,142	$2,331	$11.51	$8.26 - $21.01
Q4 2021	98,444	$2,038	$24.13	$18.26 - $31.10
Q3 2021	98,698	$2,522	$29.63	$24.31 - $35.58
Q2 2021	108,314	$3,788	$29.09	$20.22 - $37.42
Q1 2021	101,565	$3,383	$35.00	$24.47 - $53.69
Q4 2020	104,827	$2,719	$16.99	$9.97 - $29.73
Q3 2020	94,678	$934	$5.76	$3.41 - $10.11
Q2 2020	88,386	$305	$3.40	$2.54 - $4.22
Q1 2020	92,405	$283	$4.09	$2.20 - $5.44
Q4 2019	85,973	$442	$5.08	$4.37 - $5.69
Q3 2019	88,156	$460	$5.59	$4.96 - $6.21
Q2 2019	88,295	$534	$7.01	$5.80 - $7.50
Q1 2019	89,931	$650	$7.23	$6.72 - $7.46
Q4 2018	80,805	$598	$6.34	$3.90 - $7.84
Q3 2018	82,167	$445	$4.29	$3.33 - $5.82
Q2 2018	95,341	$338	$2.77	$2.02 - $4.09
Q1 2018	91,923	$189	$2.60	$2.03 - $3.43
Q4 2017	84,180	$223	$3.50	$2.51 - $5.58
Q3 2017	82,033	$431	$4.30	$3.08 - $5.70
Q2 2017	70,533	$250	$4.03	$3.11 - $5.43
Q1 2017	65,388	$339	$4.89	$3.78 - $5.74
Q4 2016	56,358	$215	$7.27	$3.76 - $9.28
Q3 2016	52,689	$473	$8.36	$6.76 - $9.50
Q2 2016	53,368	$376	$9.14	$6.79 - $10.75
Q1 2016	41,448	$362	$9.83	$7.50 - $13.98
Q4 2015	44,225	$580	$8.97	$4.26 - $14.00
Q3 2015	43,805	$161	$4.89	$3.58 - $5.90
Q2 2015	43,360	$250	$5.79	$5.11 - $6.55
Q1 2015	39,385	$230	$6.90	$5.38 - $8.78
Q4 2014	37,901	$297	$6.40	$4.52 - $8.10
Q3 2014	38,448	$189	$5.23	$4.38 - $6.42
Q2 2014	38,291	$237	$5.00	$3.87 - $6.65
Q1 2014	38,156	$204	$6.32	$4.73 - $8.20
Q4 2013	39,542	$207	$4.59	$3.47 - $5.95
Q3 2013	1,400	$8	$3.47	$2.45 - $6.50
Q2 2013	960	$2	$2.49	$1.95 - $2.94