PAIN THERAPEUTICS INC

CUSIP: 69562K100 Class: CMN

TWO SIGMA ADVISERS, LP's Holding History (CIK: 0001478735)

Note: Option positions (PUT/CALL) are excluded.

Q2 2015
Shares 13,341 Value ($000) $23 Avg Close — Range —
Q1 2015
Shares 13,241 Value ($000) $25 Avg Close — Range —
Q4 2014
Shares 13,841 Value ($000) $28 Avg Close — Range —
Q2 2014
Shares 25,841 Value ($000) $149 Avg Close — Range —
Q1 2014
Shares 14,741 Value ($000) $82 Avg Close — Range —