PLUS THERAPEUTICS INC

Ticker: PSTV CUSIP: 72941H509 Class: COM

TWO SIGMA SECURITIES, LLC's Holding History (CIK: 0001450144)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 55,883 Value ($000) $29 Avg Close $0.60 Range $0.46 - $0.94

Q3 2025

Shares 11,078 Value ($000) $8 Avg Close $0.49 Range $0.27 - $0.90

Q1 2025

Shares 13,609 Value ($000) $13 Avg Close $1.12 Range $0.24 - $2.31

Q4 2024

Shares 14,587 Value ($000) $17 Avg Close $1.28 Range $0.93 - $1.50

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	55,883	$29	$0.60	$0.46 - $0.94
Q3 2025	11,078	$8	$0.49	$0.27 - $0.90
Q1 2025	13,609	$13	$1.12	$0.24 - $2.31
Q4 2024	14,587	$17	$1.28	$0.93 - $1.50