PRAXIS PRECISION MEDICINES I

CUSIP: 74006W108 Class: Common Stock

MANUFACTURERS LIFE INSURANCE COMPANY, THE's Holding History (CIK: 0000928047)

Note: Option positions (PUT/CALL) are excluded.

Q1 2022
Shares 14,722 Value ($000) $150 Avg Close — Range —
Q4 2021
Shares 18,027 Value ($000) $355 Avg Close — Range —
Q3 2021
Shares 17,775 Value ($000) $329 Avg Close — Range —
Q2 2021
Shares 14,543 Value ($000) $266 Avg Close — Range —
Q1 2021
Shares 6,359 Value ($000) $208 Avg Close — Range —
Q4 2020
Shares 6,362 Value ($000) $350 Avg Close — Range —