PRAXIS PRECISION MEDICINES I

CUSIP: 74006W108 Class: Common Stock

Artal Group S.A.'s Holding History (CIK: 0001053906)

Note: Option positions (PUT/CALL) are excluded.

Q4 2022
Shares 1,200,000 Value ($000) $3 Avg Close — Range —
Q3 2022
Shares 1,200,000 Value ($000) $2,724 Avg Close — Range —
Q2 2022
Shares 1,200,000 Value ($000) $2,940 Avg Close — Range —
Q1 2022
Shares 1,200,000 Value ($000) $12,252 Avg Close — Range —
Q4 2021
Shares 1,200,000 Value ($000) $23,640 Avg Close — Range —
Q3 2021
Shares 1,200,000 Value ($000) $22,188 Avg Close — Range —
Q2 2021
Shares 1,200,000 Value ($000) $21,936 Avg Close — Range —
Q1 2021
Shares 750,000 Value ($000) $24,570 Avg Close — Range —
Q4 2020
Shares 750,000 Value ($000) $41,265 Avg Close — Range —