PRAXIS PRECISION MEDICINES I

CUSIP: 74006W108 Class: Common Stock

JANUS HENDERSON GROUP PLC's Holding History (CIK: 0001274173)

Note: Option positions (PUT/CALL) are excluded.

Q1 2022
Shares 3,333,943 Value ($000) $34,031 Avg Close — Range —
Q4 2021
Shares 3,342,569 Value ($000) $65,863 Avg Close — Range —
Q3 2021
Shares 3,279,165 Value ($000) $60,626 Avg Close — Range —
Q2 2021
Shares 2,978,485 Value ($000) $54,437 Avg Close — Range —
Q1 2021
Shares 1,063,389 Value ($000) $34,849 Avg Close — Range —
Q4 2020
Shares 897,372 Value ($000) $49,366 Avg Close — Range —