PRAXIS PRECISION MEDICINES I

CUSIP: 74006W108 Class: Common Stock

TWO SIGMA ADVISERS, LP's Holding History (CIK: 0001478735)

Note: Option positions (PUT/CALL) are excluded.

Q3 2023
Shares 15,700 Value ($000) $27 Avg Close — Range —
Q2 2023
Shares 24,800 Value ($000) $29 Avg Close — Range —
Q1 2023
Shares 171,900 Value ($000) $139 Avg Close — Range —
Q4 2022
Shares 447,700 Value ($000) $1,066 Avg Close — Range —
Q3 2022
Shares 503,800 Value ($000) $1,144 Avg Close — Range —
Q2 2022
Shares 221,000 Value ($000) $541 Avg Close — Range —
Q1 2022
Shares 57,300 Value ($000) $585 Avg Close — Range —
Q4 2021
Shares 62,600 Value ($000) $1,233 Avg Close — Range —
Q3 2021
Shares 30,000 Value ($000) $555 Avg Close — Range —
Q2 2021
Shares 24,100 Value ($000) $441 Avg Close — Range —