PRIME MEDICINE INC

Ticker: PRME CUSIP: 74168J101 Class: Common Stock

RA CAPITAL MANAGEMENT, L.P.'s Holding History (CIK: 0001346824)

Note: Option positions (PUT/CALL) are excluded.

Q3 2025

Shares 3,000,000 Value ($000) $16,620 Avg Close $4.06 Range $2.28 - $5.63

Period	Shares	Value ($000)	Average Close	Price Range
Q3 2025	3,000,000	$16,620	$4.06	$2.28 - $5.63