PRIME MEDICINE INC

Ticker: PRME CUSIP: 74168J101 Class: Common Stock

PRELUDE CAPITAL MANAGEMENT, LLC's Holding History (CIK: 0001387508)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 10,200 Value ($000) $35 Avg Close $4.45 Range $3.17 - $6.94

Q3 2025

Shares 22,483 Value ($000) $125 Avg Close $4.06 Range $2.28 - $5.63

Q2 2025

Shares 41,288 Value ($000) $102 Avg Close $1.54 Range $1.11 - $2.78

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	10,200	$35	$4.45	$3.17 - $6.94
Q3 2025	22,483	$125	$4.06	$2.28 - $5.63
Q2 2025	41,288	$102	$1.54	$1.11 - $2.78