PRIME MEDICINE INC

Ticker: PRME CUSIP: 74168J101 Class: Common Stock

Optiver Holding B.V.'s Holding History (CIK: 0001859606)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 160 Value ($000) $1 Avg Close $4.45 Range $3.17 - $6.94

Q3 2025

Shares 898 Value ($000) $5 Avg Close $4.06 Range $2.28 - $5.63

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	160	$1	$4.45	$3.17 - $6.94
Q3 2025	898	$5	$4.06	$2.28 - $5.63