PRIME MEDICINE INC

Ticker: PRME CUSIP: 74168J101 Class: Common Stock

Nuveen, LLC's Holding History (CIK: 0001871926)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 251,636 Value ($000) $873 Avg Close $4.45 Range $3.17 - $6.94

Q3 2025

Shares 225,843 Value ($000) $1,251 Avg Close $4.06 Range $2.28 - $5.63

Q2 2025

Shares 207,894 Value ($000) $513 Avg Close $1.54 Range $1.11 - $2.78

Q1 2025

Shares 59,402 Value ($000) $374 Avg Close $2.55 Range $1.65 - $3.59

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	251,636	$873	$4.45	$3.17 - $6.94
Q3 2025	225,843	$1,251	$4.06	$2.28 - $5.63
Q2 2025	207,894	$513	$1.54	$1.11 - $2.78
Q1 2025	59,402	$374	$2.55	$1.65 - $3.59