PRINCIPIA BIOPHARMA INC

CUSIP: 74257L108 Class: COM

ADAGE CAPITAL PARTNERS GP, L.L.C.'s Holding History (CIK: 0001165408)

Note: Option positions (PUT/CALL) are excluded.

Q2 2020
Shares 819,160 Value ($000) $48,978 Avg Close — Range —
Q1 2020
Shares 865,000 Value ($000) $51,364 Avg Close — Range —
Q4 2019
Shares 500,000 Value ($000) $27,390 Avg Close — Range —
Q3 2019
Shares 400,000 Value ($000) $11,296 Avg Close — Range —
Q2 2019
Shares 500,000 Value ($000) $16,595 Avg Close — Range —
Q1 2019
Shares 700,000 Value ($000) $23,800 Avg Close — Range —
Q4 2018
Shares 700,000 Value ($000) $19,173 Avg Close — Range —
Q3 2018
Shares 300,000 Value ($000) $8,766 Avg Close — Range —