PRINCIPIA BIOPHARMA INC

CUSIP: 74257L108 Class: COM

TWO SIGMA INVESTMENTS, LP's Holding History (CIK: 0001179392)

Note: Option positions (PUT/CALL) are excluded.

Q2 2020
Shares 129,893 Value ($000) $7,766 Avg Close — Range —
Q1 2020
Shares 59,918 Value ($000) $3,558 Avg Close — Range —
Q4 2019
Shares 25,848 Value ($000) $1,416 Avg Close — Range —