PRONAI THERAPEUTICS INC

CUSIP: 74346L101 Class: COM

MANUFACTURERS LIFE INSURANCE COMPANY, THE's Holding History (CIK: 0000928047)

Note: Option positions (PUT/CALL) are excluded.

Q4 2016
Shares 791 Value ($000) $1 Avg Close — Range —
Q3 2016
Shares 791 Value ($000) $1 Avg Close — Range —
Q2 2016
Shares 791 Value ($000) $2 Avg Close — Range —
Q1 2016
Shares 791 Value ($000) $6 Avg Close — Range —