PRONAI THERAPEUTICS INC

CUSIP: 74346L101 Class: COM

TWO SIGMA SECURITIES, LLC's Holding History (CIK: 0001450144)

Note: Option positions (PUT/CALL) are excluded.

Q4 2016
Shares 13,226 Value ($000) $20 Avg Close — Range —
Q3 2016
Shares 12,822 Value ($000) $23 Avg Close — Range —