PROMETHEUS BIOSCIENCES INC

CUSIP: 74349U108 Class: Common Stock

TWO SIGMA ADVISERS, LP's Holding History (CIK: 0001478735)

Note: Option positions (PUT/CALL) are excluded.

Q1 2023
Shares 89,000 Value ($000) $9,551 Avg Close — Range —
Q4 2022
Shares 135,100 Value ($000) $14,861 Avg Close — Range —
Q3 2022
Shares 130,000 Value ($000) $7,671 Avg Close — Range —
Q2 2022
Shares 25,000 Value ($000) $706 Avg Close — Range —