PROTALIX BIOTHERAPEUTICS INC

Ticker: PLX CUSIP: 74365A309 Class: Common Stock

TWO SIGMA SECURITIES, LLC's Holding History (CIK: 0001450144)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 39,811 Value ($000) $72 Avg Close $2.04 Range $1.60 - $2.66

Q2 2024

Shares 52,320 Value ($000) $61 Avg Close $1.18 Range $1.03 - $1.37

Q1 2024

Shares 85,313 Value ($000) $107 Avg Close $1.49 Range $1.21 - $1.85

Q4 2023

Shares 44,474 Value ($000) $79 Avg Close $1.56 Range $1.21 - $1.90

Q2 2023

Shares 15,276 Value ($000) $31 Avg Close $2.38 Range $1.90 - $3.55

Q1 2023

Shares 20,760 Value ($000) $44 Avg Close $1.75 Range $1.32 - $2.21

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	39,811	$72	$2.04	$1.60 - $2.66
Q2 2024	52,320	$61	$1.18	$1.03 - $1.37
Q1 2024	85,313	$107	$1.49	$1.21 - $1.85
Q4 2023	44,474	$79	$1.56	$1.21 - $1.90
Q2 2023	15,276	$31	$2.38	$1.90 - $3.55
Q1 2023	20,760	$44	$1.75	$1.32 - $2.21